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Multiple Choice

What is the recommended immediate treatment for asystole during ACLS?

Asystole is a non-shockable rhythm, so the priority is to restore perfusion rather than deliver a shock. The best immediate treatment is high-quality CPR to maintain blood flow to the heart and brain, paired with epinephrine given at 3–5 minute intervals to improve coronary and cerebral perfusion pressures during CPR. Defibrillation isn’t used because there’s no electrical activity to shock. Medications like amiodarone are reserved for shockable rhythms (VT/VF) after failed defibrillation, and atropine isn’t routinely used for pulseless asystole. Simultaneously, search for reversible causes (the Hs and Ts) and continue CPR until return of spontaneous circulation or termination of effort.

Asystole is a non-shockable rhythm, so the priority is to restore perfusion rather than deliver a shock. The best immediate treatment is high-quality CPR to maintain blood flow to the heart and brain, paired with epinephrine given at 3–5 minute intervals to improve coronary and cerebral perfusion pressures during CPR. Defibrillation isn’t used because there’s no electrical activity to shock. Medications like amiodarone are reserved for shockable rhythms (VT/VF) after failed defibrillation, and atropine isn’t routinely used for pulseless asystole. Simultaneously, search for reversible causes (the Hs and Ts) and continue CPR until return of spontaneous circulation or termination of effort.