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Multiple Choice

Lateral wall ischemia is detected by ST depression and T-wave inversion in which leads?

Lateral wall ischemia shows ST depression and T-wave inversion in the leads that view the left lateral ventricle: those are leads I, aVL, V5, and V6. When the lateral wall becomes ischemic, subendocardial injury in that region typically yields downward or horizontal ST segment depression with T-wave inversion in these lateral leads. This distribution aligns with the territory supplied by the left circumflex artery. In contrast, inferior-wall ischemia would produce changes in leads II, III, and aVF, and anterior-wall ischemia in V1-V4. ST elevation would suggest transmural, not subendocardial, ischemia, which is not what’s described here.

Lateral wall ischemia shows ST depression and T-wave inversion in the leads that view the left lateral ventricle: those are leads I, aVL, V5, and V6. When the lateral wall becomes ischemic, subendocardial injury in that region typically yields downward or horizontal ST segment depression with T-wave inversion in these lateral leads. This distribution aligns with the territory supplied by the left circumflex artery. In contrast, inferior-wall ischemia would produce changes in leads II, III, and aVF, and anterior-wall ischemia in V1-V4. ST elevation would suggest transmural, not subendocardial, ischemia, which is not what’s described here.