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Multiple Choice

Lateral ischemia on ECG is suggested by ST depression and T-wave inversion in which leads?

Lateral ischemia affects the lateral wall of the left ventricle, which is viewed by leads I, aVL, V5, and V6. When this region becomes ischemic, the subendocardial injury current alters repolarization, producing ST-segment depression and T-wave inversion in those lateral-viewing leads. This pattern distinguishes lateral ischemia from ischemia in other regions: inferior ischemia shows changes in II, III, aVF, while anterior/septal ischemia shows changes in V1-V3.

Lateral ischemia affects the lateral wall of the left ventricle, which is viewed by leads I, aVL, V5, and V6. When this region becomes ischemic, the subendocardial injury current alters repolarization, producing ST-segment depression and T-wave inversion in those lateral-viewing leads. This pattern distinguishes lateral ischemia from ischemia in other regions: inferior ischemia shows changes in II, III, aVF, while anterior/septal ischemia shows changes in V1-V3.