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Multiple Choice

In STEMI, reciprocal changes are seen where?

Reciprocal changes are ST-segment depressions in leads that mirror the area of the heart opposite the infarct. In STEMI, the injured, transmurally affected myocardium generates an injury current that causes ST elevation in the leads facing that region. The opposite walls experience a current in the opposite direction, producing ST depression in the opposite leads. This pattern helps localize the infarct and is especially common when the infarct is large. For example, an inferior-wall STEMI (where ST elevation is seen in the inferior leads) often has reciprocal ST depression in the anterior leads. The other options don’t describe this reciprocal phenomenon: PR depressions are more typical of pericarditis, diffuse T-wave inversions can occur later in evolution, and ST elevations in infarct-related leads describe the primary injury, not the reciprocal pattern.

Reciprocal changes are ST-segment depressions in leads that mirror the area of the heart opposite the infarct. In STEMI, the injured, transmurally affected myocardium generates an injury current that causes ST elevation in the leads facing that region. The opposite walls experience a current in the opposite direction, producing ST depression in the opposite leads. This pattern helps localize the infarct and is especially common when the infarct is large.

For example, an inferior-wall STEMI (where ST elevation is seen in the inferior leads) often has reciprocal ST depression in the anterior leads. The other options don’t describe this reciprocal phenomenon: PR depressions are more typical of pericarditis, diffuse T-wave inversions can occur later in evolution, and ST elevations in infarct-related leads describe the primary injury, not the reciprocal pattern.