In Brugada syndrome, the ST-segment elevation is most characteristic in which leads?

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Multiple Choice

In Brugada syndrome, the ST-segment elevation is most characteristic in which leads?

In Brugada syndrome, the ST-segment elevation localizes to the right precordial leads, especially the area over the right ventricle. The classic pattern shows up most prominently in V1 and V2, and often V3, reflecting the right ventricular outflow tract substrate where the abnormal repolarization occurs. This is why the ST elevation is described as being most characteristic in those leads. The other lead groups don’t typically show the Brugada pattern: inferior leads (II, III, aVF) look for patterns associated with other conditions, and left precordial leads (V4–V6) reflect the left ventricle, where Brugada changes are not the characteristic finding. Therefore, recognizing the right precordial localization in V1–V3 is key to identifying Brugada-type ST elevations.

In Brugada syndrome, the ST-segment elevation localizes to the right precordial leads, especially the area over the right ventricle. The classic pattern shows up most prominently in V1 and V2, and often V3, reflecting the right ventricular outflow tract substrate where the abnormal repolarization occurs. This is why the ST elevation is described as being most characteristic in those leads.

The other lead groups don’t typically show the Brugada pattern: inferior leads (II, III, aVF) look for patterns associated with other conditions, and left precordial leads (V4–V6) reflect the left ventricle, where Brugada changes are not the characteristic finding. Therefore, recognizing the right precordial localization in V1–V3 is key to identifying Brugada-type ST elevations.

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