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Multiple Choice

In an anterior STEMI, reciprocal changes are typically seen in which leads?

Reciprocal changes arise when the current of injury from an infarct is best seen in opposite leads. In an anterior STEMI, the affected territory is the anterior wall (LAD territory), so ST elevation shows in the anterior-facing leads V1–V4. The opposite wall is the inferior region, which is reflected in leads II, III, and aVF. Those inferior leads often show ST-segment depression—the reciprocal changes of the anterior injury. If you’re thinking about other patterns, a posterior MI would show ST elevation in posterior leads (V7–V9) with reciprocal depression in the anterior leads, and right ventricular involvement often involves the right-sided lead V4R rather than being a reciprocal change of the anterior territory.

Reciprocal changes arise when the current of injury from an infarct is best seen in opposite leads. In an anterior STEMI, the affected territory is the anterior wall (LAD territory), so ST elevation shows in the anterior-facing leads V1–V4. The opposite wall is the inferior region, which is reflected in leads II, III, and aVF. Those inferior leads often show ST-segment depression—the reciprocal changes of the anterior injury.

If you’re thinking about other patterns, a posterior MI would show ST elevation in posterior leads (V7–V9) with reciprocal depression in the anterior leads, and right ventricular involvement often involves the right-sided lead V4R rather than being a reciprocal change of the anterior territory.