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Multiple Choice

How can LVH with strain be recognized on ECG?

Recognizing LVH with strain hinges on a repolarization abnormality that accompanies increased left ventricular mass. When the ventricle is hypertrophied, the repolarization vector shifts, especially in the lateral leads, producing downsloping ST depression and T-wave inversion—the classic strain pattern. These lateral leads (I, aVL, V5, V6) are where this change is most evident, reflecting the outer left ventricular wall where the strain from hypertrophy is most pronounced. Other patterns point to different problems: a short PR interval suggests pre-excitation or fast conduction syndromes; Q waves in inferior leads imply prior infarction; ST elevations in the inferior leads indicate an acute inferior myocardial infarction. So the hallmark of LVH with strain is downsloping ST depression with T-wave inversion in the lateral leads.

Recognizing LVH with strain hinges on a repolarization abnormality that accompanies increased left ventricular mass. When the ventricle is hypertrophied, the repolarization vector shifts, especially in the lateral leads, producing downsloping ST depression and T-wave inversion—the classic strain pattern. These lateral leads (I, aVL, V5, V6) are where this change is most evident, reflecting the outer left ventricular wall where the strain from hypertrophy is most pronounced.

Other patterns point to different problems: a short PR interval suggests pre-excitation or fast conduction syndromes; Q waves in inferior leads imply prior infarction; ST elevations in the inferior leads indicate an acute inferior myocardial infarction. So the hallmark of LVH with strain is downsloping ST depression with T-wave inversion in the lateral leads.